Ontology highlight
ABSTRACT:
SUBMITTER: Lamichhane S
PROVIDER: S-EPMC6359525 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Lamichhane Santosh S Ahonen Linda L Dyrlund Thomas Sparholt TS Dickens Alex M AM Siljander Heli H Hyöty Heikki H Ilonen Jorma J Toppari Jorma J Veijola Riitta R Hyötyläinen Tuulia T Knip Mikael M Oresic Matej M
Biomolecules 20190121 1
Previous studies suggest that children who progress to type 1 diabetes (T1D) later in life already have an altered serum lipid molecular profile at birth. Here, we compared cord blood lipidome across the three study groups: children who progressed to T1D (PT1D; <i>n</i> = 30), children who developed at least one islet autoantibody but did not progress to T1D during the follow-up (P1Ab; <i>n</i> = 33), and their age-matched controls (CTR; <i>n</i> = 38). We found that phospholipids, specifically ...[more]