Rapid task-dependent tuning of the mouse olfactory bulb.
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ABSTRACT:
SUBMITTER: Koldaeva A
PROVIDER: S-EPMC6365054 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Publications
Rapid task-dependent tuning of the mouse olfactory bulb.
Koldaeva Anzhelika A Schaefer Andreas T AT Fukunaga Izumi I
eLife 20190206
Adapting neural representation to rapidly changing behavioural demands is a key challenge for the nervous system. Here, we demonstrate that the output of the primary olfactory area of the mouse, the olfactory bulb, is already a target of dynamic and reproducible modulation. The modulation depends on the stimulus tuning of a given neuron, making olfactory responses more discriminable through selective amplification in a demand-specific way. ...[more]
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