Ontology highlight
ABSTRACT:
SUBMITTER: Herzik MA
PROVIDER: S-EPMC6365196 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Herzik Mark A MA Fraser James S JS Lander Gabriel C GC
Structure (London, England : 1993) 20181115 2
There does not currently exist a standardized indicator of how well cryo-EM-derived models represent the density from which they were generated. We present a straightforward methodology that utilizes freely available tools to generate a suite of independent models and to evaluate their convergence in an EM density. These analyses provide both a quantitative and qualitative assessment of the precision of the models and their representation of the density, respectively, while concurrently providin ...[more]