Dissociating polysensitization and multimorbidity in children and adults from a Polish general population cohort.
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ABSTRACT: Background
Links between multimorbidity of allergic diseases and allergen sensitization are still under debate, especially in adults. This study aimed to establish a relationship between polysensitization and allergic multimorbidity in children and adults and the allergens involved in multimorbidity.Material and method
A cross-sectional multicentre study enrolled children aged 6-7 and 13-14 years and adults aged 20-44 years from a Polish national cohort. The diagnosis of allergic diseases was made by a physician. Skin prick tests to 13 allergens and serum IgE levels to 4 allergens were tested.Results
Among the 3856 participants, single disease (asthma, allergic rhinitis or atopic dermatitis) was diagnosed in 27.7% subjects and allergic multimorbidity in 9.3%. Allergic multimorbidity occurred more commonly in children than in adults (p?ConclusionsMultimorbidity is associated with polysensitization especially in children compared with adults in Polish population cohort. New insights into single disease patterns were found: bronchial asthma is the strongest risk factor for the development of multimorbidity in comparison with allergic rhinitis and atopic dermatitis.
SUBMITTER: Raciborski F
PROVIDER: S-EPMC6369558 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Dissociating polysensitization and multimorbidity in children and adults from a Polish general population cohort.
Raciborski Filip F Bousquet Jean J Bousqet Jean J Namysłowski Andrzej A Krzych-Fałta Edyta E Tomaszewska Aneta A Piekarska Barbara B Samel-Kowalik Piotr P Białoszewski Artur Z AZ Walkiewicz Artur A Lipiec Agnieszka A Wojas Oksana O Samoliński Krzysztof K Szylling Anna A Zieliński Wojciech W Sybilski Adam A Grąbczewska Aleksandra A Samoliński Bolesław B
Clinical and translational allergy 20190211
<h4>Background</h4>Links between multimorbidity of allergic diseases and allergen sensitization are still under debate, especially in adults. This study aimed to establish a relationship between polysensitization and allergic multimorbidity in children and adults and the allergens involved in multimorbidity.<h4>Material and method</h4>A cross-sectional multicentre study enrolled children aged 6-7 and 13-14 years and adults aged 20-44 years from a Polish national cohort. The diagnosis of allergic ...[more]
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