Ontology highlight
ABSTRACT:
SUBMITTER: Shahabi P
PROVIDER: S-EPMC6375065 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Shahabi Payman P Scheinfeldt Laura B LB Lynch Daniel E DE Schmidlen Tara J TJ Perreault Sylvie S Keller Margaret A MA Kasper Rachel R Wawak Lisa L Jarvis Joseph P JP Gerry Norman P NP Gordon Erynn S ES Christman Michael F MF Dubé Marie-Pierre MP Gharani Neda N
Thrombosis and haemostasis 20160428 2
Pharmacogenomics (PGx) guided warfarin dosing, using a comprehensive dosing algorithm, is expected to improve dose optimisation and lower the risk of adverse drug reactions. As a complementary tool, a simple genotype-dosing table, such as in the US Food and Drug Administration (FDA) Coumadin drug label, may be utilised for general risk assessment of likely over- or under-anticoagulation on a standard dose of warfarin. This tool may be used as part of the clinical decision support for the interpr ...[more]