Ontology highlight
ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC6385178 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Wu You Y Shi Wanyue W Tang Tingting T Wang Yidong Y Yin Xin X Chen Yanlin Y Zhang Yanfeng Y Xing Yun Y Shen Yumeng Y Xia Tiansong T Guo Changying C Pan Yi Y Jin Liang L
Cell death & disease 20190221 3
Breast cancer is the most prevalent cancer in women worldwide, which remains incurable once metastatic. Breast cancer stem cells (BCSCs) are a small subset of breast cancer cells which are essential in tumor formation, metastasis, and drug resistance. microRNAs (miRNAs) play important roles in the breast cancer cells and BCSCs by regulating specific genes. In this study, we found that miR-29a was up-regulated in BCSCs, in aggressive breast cancer cell line and in breast cancer tissues. We also c ...[more]