Ontology highlight
ABSTRACT:
SUBMITTER: Turcios L
PROVIDER: S-EPMC6386480 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Turcios Lilia L Chacon Eduardo E Garcia Catherine C Eman Pedro P Cornea Virgilius V Jiang Jieyun J Spear Brett B Liu Chunming C Watt David S DS Marti Francesc F Gedaly Roberto R
PloS one 20190222 2
Autophagy targets cellular components for lysosomal-dependent degradation in which the products of degradation may be recycled for protein synthesis and utilized for energy production. Autophagy also plays a critical role in cell homeostasis and the regulation of many physiological and pathological processes and prompts this investigation of new agents to effect abnormal autophagy in hepatocellular carcinoma (HCC). 2,5-Dichloro-N-(2-methyl-4-nitrophenyl) benzenesulfonamide (FH535) is a synthetic ...[more]