Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer.
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ABSTRACT:
SUBMITTER: Zhao R
PROVIDER: S-EPMC6389063 | biostudies-literature | 2018 Feb
REPOSITORIES: biostudies-literature
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Exosomal long noncoding RNA HOTTIP as potential novel diagnostic and prognostic biomarker test for gastric cancer.
Zhao Rui R Zhang Yanli Y Zhang Xin X Yang Yongmei Y Zheng Xin X Li Xiaohui X Liu Yingjie Y Zhang Yi Y
Molecular cancer 20180227 1
Long noncoding RNA HOTTIP plays important roles in the generation and progression of human cancers. Exosomes participate in cellular communication by transmitting moleculars between cells and are regarded as suitable candidates for non-invasive diagnosis. However, the existence of HOTTIP in the circulating exosomes and the potential roles of exosomal HOTTIP in gastric cancer (GC) was poorly understood. This study aims at investigating the clinical roles of exosomal HOTTIP in GC. Serum exosomal H ...[more]
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