Ontology highlight
ABSTRACT:
SUBMITTER: Tester DJ
PROVIDER: S-EPMC6394853 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
The Journal of pediatrics 20180926
<h4>Objective</h4>To determine whether a monogenic basis explains sudden infant death syndrome (SIDS) using an exome-wide focus.<h4>Study design</h4>A cohort of 427 unrelated cases of SIDS (257 male; average age = 2.7 ± 1.9 months) underwent whole-exome sequencing. Exome-wide rare variant analyses were carried out with 278 SIDS cases of European ancestry (173 male; average age = 2.7 ± 1.98 months) and 973 ethnic-matched controls based on 6 genetic models. Ingenuity Pathway Analysis also was perf ...[more]