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Transcriptomic analysis of neuroinflammation and occult infection in sudden infant death syndrome

ABSTRACT: Antemortem infection is a risk factor for sudden infant death syndrome (SIDS) – the leading postneonatal cause of infant mortality in the developed world. Manifestations of infection and attendant inflammation, however, are not always apparent in clinical settings or by standard autopsy, thus enhanced resolution approaches are needed. Here we screened postmortem SIDS tissues and fluids for inflammatory markers and applied metagenomics and transcriptomics to a subset of cases to look for evidence of occult infection and inflammation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE245891 | GEO | 2024/01/04

REPOSITORIES: GEO

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