Ontology highlight
ABSTRACT:
SUBMITTER: Scholz N
PROVIDER: S-EPMC6400551 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Scholz Nicole N Ehmann Nadine N Sachidanandan Divya D Imig Cordelia C Cooper Benjamin H BH Jahn Olaf O Reim Kerstin K Brose Nils N Meyer Jutta J Lamberty Marius M Altrichter Steffen S Bormann Anne A Hallermann Stefan S Pauli Martin M Heckmann Manfred M Stigloher Christian C Langenhan Tobias T Kittel Robert J RJ
The Journal of cell biology 20190219 3
Information processing by the nervous system depends on neurotransmitter release from synaptic vesicles (SVs) at the presynaptic active zone. Molecular components of the cytomatrix at the active zone (CAZ) regulate the final stages of the SV cycle preceding exocytosis and thereby shape the efficacy and plasticity of synaptic transmission. Part of this regulation is reflected by a physical association of SVs with filamentous CAZ structures via largely unknown protein interactions. The very C-term ...[more]