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Novel PSMA-Coated On-Off-On Fluorescent Chemosensor Based on Organic Dots with AIEgens for Detection of Copper (II), Iron (III) and Cysteine.

ABSTRACT: Herein, a novel on-off-on fluorescent chemosensor for copper (II) ion (Cu²⁺), iron (III) ion (Fe³⁺) and cysteine is developed simply by the nano-precipitation method. The prepared organic dots with AIEgens (AIE dots) are advantageous over other metal ions in detecting Cu²⁺, Fe³⁺ with high selectivity and sensitivity by forming agglomerations (on-off). The agglomerations formed by AIE dots and Cu²⁺ redistributed and the fluorescence was obviously recovered in the presence of cysteine (off-on). This sensor has a wide linear range for Cu²⁺, Fe³⁺ and cysteine. The fluorescent detection limits of AIE dots are calculated to be 107 nM for Cu²⁺, 120 nM for Fe³⁺ and 78 nM for cysteine, respectively. These results indicate that the AIE dots can be used as a potential probe for Cu²⁺, Fe³⁺ and cysteine detection.

SUBMITTER: Jiang R

PROVIDER: S-EPMC6403782 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Novel PSMA-Coated On-Off-On Fluorescent Chemosensor Based on Organic Dots with AIEgens for Detection of Copper (II), Iron (III) and Cysteine.

Jiang Rui R Liu Na N Li Fan F Fu Wensheng W Zhou Yun Y Zhang Yan Y

Polymers 20180717 7

Herein, a novel on-off-on fluorescent chemosensor for copper (II) ion (Cu2+), iron (III) ion (Fe3+) and cysteine is developed simply by the nano-precipitation method. The prepared organic dots with AIEgens (AIE dots) are advantageous over other metal ions in detecting Cu2+, Fe3+ with high selectivity and sensitivity by forming agglomerations (on-off). The agglomerations formed by AIE dots and Cu2+ redistributed and the fluorescence was obvio ...[more]

PMID: 30960711

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