MiR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years.
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ABSTRACT:
SUBMITTER: Tacke F
PROVIDER: S-EPMC6409014 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
miR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years.
Tacke Frank F Spehlmann Martina E ME Vucur Mihael M Benz Fabian F Luedde Mark M Cardenas David Vargas DV Roy Sanchari S Loosen Sven S Hippe Hans-Joerg HJ Frey Norbert N Trautwein Christian C Koch Alexander A Roderburg Christoph C Luedde Tom T
Mediators of inflammation 20190224
<h4>Introduction</h4>Alterations in miR-155 serum levels have been described in inflammatory and infectious diseases. Moreover, a role for miR-155 in aging and age-related diseases was recently suggested. We therefore analyzed a potential age-dependent prognostic value of circulating miR-155 as a serum-based marker in critical illness.<h4>Methods</h4>Concentrations of circulating miR-155 were determined in 218 critically ill patients and 76 healthy controls.<h4>Results</h4>By using qPCR, we demo ...[more]
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