Ontology highlight
ABSTRACT:
SUBMITTER: Song J
PROVIDER: S-EPMC6409610 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Song Juan J Chi Miaomiao M Luo Xiaonuan X Song Qinqin Q Xia Dong D Shi Bingtian B Han Jun J
Viruses 20190201 2
To understand the underlying mechanisms of endoplasmic reticulum (ER) stress caused by human rhinovirus (HRV) 16 and non-structural transmembrane protein 2B, the expressions of ER chaperone glucose-regulated protein 78 (GRP78) and three signal transduction pathways, including protein kinase RNA-like ER kinase (PERK), activating transcription factor 6 (ATF6) and inositol-requiring enzyme 1 (IRE1), were evaluated after HRV16 infection and 2B gene transfection. Our results showed that both HRV16 in ...[more]