Ontology highlight
ABSTRACT:
SUBMITTER: Wilckens KA
PROVIDER: S-EPMC6416050 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Neurobiology of aging 20180726
Amyloid-β (Aβ) accumulation is a hallmark of Alzheimer's disease, although Aβ alone may be insufficient to cause impairments. Modifiable health factors, including sleep, may mitigate functional symptoms of neurodegeneration. We assessed whether sleep moderated the relationship between Aβ and cognitive performance in 41 older adults, mean age 83 years. Sleep measures included actigraphy-assessed wake after sleep onset and total sleep time. Cognitive performance was assessed with memory recall, co ...[more]