Ontology highlight
ABSTRACT:
SUBMITTER: Ali AT
PROVIDER: S-EPMC6420317 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Ali Aminah T AT Boehme Lena L Carbajosa Guillermo G Seitan Vlad C VC Small Kerrin S KS Hodgkinson Alan A
eLife 20190218
Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 tissue/cell types, we find considerable variation in mitochondrial-encoded gene expression along the mitochondrial transcriptome, across tissues and between individuals, highlighting the importance of cell-type specific and post-transcriptional proces ...[more]