Ontology highlight
ABSTRACT:
SUBMITTER: Wang YJ
PROVIDER: S-EPMC6436557 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Wang Yue J YJ Traum Daniel D Schug Jonathan J Gao Long L Liu Chengyang C Atkinson Mark A MA Powers Alvin C AC Feldman Michael D MD Naji Ali A Chang Kyong-Mi KM Kaestner Klaus H KH
Cell metabolism 20190131 3
The interaction between the immune system and endocrine cells in the pancreas is crucial for the initiation and progression of type 1 diabetes (T1D). Imaging mass cytometry (IMC) enables multiplexed assessment of the abundance and localization of more than 30 proteins on the same tissue section at 1-μm resolution. Herein, we have developed a panel of 33 antibodies that allows for the quantification of key cell types including pancreatic exocrine cells, islet cells, immune cells, and stromal comp ...[more]