Ontology highlight
ABSTRACT:
SUBMITTER: Huang X
PROVIDER: S-EPMC6438033 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Huang Xiaoli X Feng Yang Y Xiong Guanqing G Whyte Shona S Duan Jing J Yang Yucen Y Wang Kaiyu K Yang Shiyong S Geng Yi Y Ou Yangping Y Chen Defang D
Cell & bioscience 20190327
Pyroptosis, a type of programmed cell death that along with inflammation, is mainly regulated by two main pathways, cysteinyl aspartate specific proteinase (caspase)-1-induced canonical inflammatory pathway and caspase-11-induced non-canonical inflammatory pathway. The non-canonical inflammatory pathway-induced pyroptosis is a unique immune response in response to gram-negative (G<sup>-</sup>) bacteria. It is induced by lipopolysaccharide (LPS) on the surface of G<sup>-</sup> bacteria. This acti ...[more]