Ontology highlight
ABSTRACT:
SUBMITTER: Pan CW
PROVIDER: S-EPMC6456419 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Pan Ching W CW Horvath Daniel G DG Braza Samuel S Moore Trevor T Lynch Annabella A Feit Cameron C Abbyad Paul P
Lab on a chip 20190401 8
Selection of live cells from a population is critical in many biological studies and biotechnologies. We present here a novel droplet microfluidic approach that allows for label-free and passive selection of live cells using the glycolytic activity of individual cells. It was observed that with the use of a specific surfactant utilized to stabilize droplet formation, the interfacial tension of droplets was very sensitive to pH. After incubation, cellular lactate release results in droplets conta ...[more]