Ontology highlight
ABSTRACT:
SUBMITTER: Millham AB
PROVIDER: S-EPMC6465167 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Organic letters 20190107 2
A complementary process to the Pauson-Khand annulation is described that is well suited to forging densely substituted/oxygenated cyclopentenone products (including fully substituted variants). The reaction is thought to proceed through a sequence of metallacycle-mediated bond-forming events that engages an internal alkyne and a β-keto ester in an annulation process that forges two C-C bonds. A variant of this annulation process has also been established that delivers deoxygenated cyclopentenone ...[more]