Ontology highlight
ABSTRACT:
SUBMITTER: Sibai M
PROVIDER: S-EPMC6470016 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Sibai Mira M Wirth Dennis J DJ Leblond Frederic F Roberts David W DW Paulsen Keith D KD Wilson Brian C BC
Journal of biophotonics 20190320 5
The rate of complete resection of glioma has improved with the introduction of 5-aminolevulinic acid-induced protoporphyrin IX (PpIX) fluorescence image guidance. Surgical outcomes are further enhanced when the fluorescence signal is decoupled from the intrinsic tissue optical absorption and scattering obtained from diffuse reflectance measurements, yielding the absolute PpIX concentration, [PpIX]. Spatial frequency domain imaging was used previously to measure [PpIX] in near-surface tumors unde ...[more]