Ontology highlight
ABSTRACT:
SUBMITTER: Dou F
PROVIDER: S-EPMC6471136 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Dou Fangmin F Wang Zhi Z Li Guiying G Dun Baoqing B
Molecules (Basel, Switzerland) 20190315 6
Glycosylation is an efficient strategy to modulate the solubility, stability, bioavailability and bioactivity of drug-like natural products. Biological methods, such as whole-cell biocatalyst, promise a simple but highly effective approach to glycosylate biologically active small molecules with remarkable regio- and stereo-selectivity. Herein, we use the entomopathogenic filamentous fungus <i>Isaria fumosorosea</i> ACCC 37814 to biotransform a panel of phenolic natural products, including flavon ...[more]