Ontology highlight
ABSTRACT:
SUBMITTER: Deller RC
PROVIDER: S-EPMC6478844 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Deller Robert C RC Richardson Thomas T Richardson Rebecca R Bevan Laura L Zampetakis Ioannis I Scarpa Fabrizio F Perriman Adam W AW
Nature communications 20190423 1
Cell membrane re-engineering is emerging as a powerful tool for the development of next generation cell therapies, as it allows the user to augment therapeutic cells to provide additional functionalities, such as homing, adhesion or hypoxia resistance. To date, however, there are few examples where the plasma membrane is re-engineered to display active enzymes that promote extracellular matrix protein assembly. Here, we report on a self-contained matrix-forming system where the membrane of human ...[more]