Ontology highlight
ABSTRACT:
SUBMITTER: Agostinis C
PROVIDER: S-EPMC6479455 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Agostinis Chiara C Masat Elisa E Bossi Fleur F Ricci Giuseppe G Menegazzi Renzo R Lombardelli Letizia L Zito Gabriella G Mangogna Alessandro A Degan Massimo M Gattei Valter V Piccinni Marie-Pierre MP Kishore Uday U Bulla Roberta R
International journal of molecular sciences 20190331 7
<h4>Background</h4>In pregnancy, excessive inflammation and break down of immunologic tolerance can contribute to miscarriage. Endothelial cells (ECs) are able to orchestrate the inflammatory processes by secreting pro-inflammatory mediators and bactericidal factors by modulating leakiness and leukocyte trafficking, via the expression of adhesion molecules and chemokines. The aim of this study was to analyse the differences in the phenotype between microvascular ECs isolated from decidua (DECs) ...[more]