Ontology highlight
ABSTRACT:
SUBMITTER: Aliperti V
PROVIDER: S-EPMC6479754 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Aliperti Vincenza V Sgueglia Giulia G Aniello Francesco F Vitale Emilia E Fucci Laura L Donizetti Aldo A
International journal of molecular sciences 20190328 7
EGR1 is a transcription factor expressed in many cell types that regulates genes involved in different biological processes including growth, proliferation, and apoptosis. Dysregulation of EGR1 expression has been associated with many pathological conditions such as tumors and brain diseases. Known molecular mechanisms underlying the control of EGR1 function include regulation of transcription, mRNA and protein stability, and post-translational modifications. Here we describe the identification ...[more]