Ontology highlight
ABSTRACT:
SUBMITTER: Huang Y
PROVIDER: S-EPMC6481603 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20190206 9
Racemic vinylallenes are shown to be effective substrates for catalytic multicomponent diastereo- and enantioselective 1,6-conjugate addition of multifunctional allyl moieties to easily accessible α,β,γ,δ-unsaturated diesters. Reactions may be catalyzed by 5.0 mol % of a readily accessible NHC-Cu complex at ambient temperature, and other than a vinylallene, involve B<sub>2</sub> (pin)<sub>2</sub> and an α,β,γ,δ-unsaturated diester. A variety of vinylallenes were converted to products bearing a Z ...[more]