Ontology highlight
ABSTRACT:
SUBMITTER: Le DHT
PROVIDER: S-EPMC6485256 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Le Duc H T DHT Méndez-López Eduardo E Wang Chao C Commandeur Ulrich U Aranda Miguel A MA Steinmetz Nicole F NF
Biomacromolecules 20181218 1
Nanoparticles with high aspect ratios have favorable attributes for drug delivery and bioimaging applications based on their enhanced tissue penetration and tumor homing properties. Here, we investigated a novel filamentous viral nanoparticle (VNP) based on the Pepino mosaic virus (PepMV), a relative of the established platform Potato virus X (PVX). We studied the chemical reactivity of PepMV, produced fluorescent versions of PepMV and PVX, and then evaluated their biodistribution in mouse tumor ...[more]