Ontology highlight
ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC6487681 | biostudies-literature | 2019 Apr
REPOSITORIES: biostudies-literature
Wang Xiaomeng X Liu Hongliang H Xu Yinghui Y Xie Jichun J Zhu Dakai D Amos Christopher I CI Fang Shenying S Lee Jeffrey E JE Li Xin X Nan Hongmei H Song Yanqiu Y Wei Qingyi Q
Carcinogenesis 20190401 2
Remodeling or deregulation of the calcium signaling pathway is a relevant hallmark of cancer including cutaneous melanoma (CM). In this study, using data from a published genome-wide association study (GWAS) from The University of Texas M.D. Anderson Cancer Center, we assessed the role of 41,377 common single-nucleotide polymorphisms (SNPs) of 167 calcium signaling pathway genes in CM survival. We used another GWAS from Harvard University as the validation dataset. In the single-locus analysis, ...[more]