Ontology highlight
ABSTRACT:
SUBMITTER: Crerar H
PROVIDER: S-EPMC6509357 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Crerar Hamish H Scott-Solomon Emily E Bodkin-Clarke Chantal C Andreassi Catia C Hazbon Maria M Logie Emilie E Cano-Jaimez Marifé M Gaspari Marco M Kuruvilla Rejji R Riccio Antonella A
Neuron 20190307 3
Neurons are extraordinarily large and highly polarized cells that require rapid and efficient communication between cell bodies and axons over long distances. In peripheral neurons, transcripts are transported along axons to growth cones, where they are rapidly translated in response to extrinsic signals. While studying Tp53inp2, a transcript highly expressed and enriched in sympathetic neuron axons, we unexpectedly discovered that Tp53inp2 is not translated. Instead, the transcript supports axo ...[more]