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Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid antibodies.

ABSTRACT:

SUBMITTER: Bala MM

PROVIDER: S-EPMC6513409 | biostudies-literature | 2018 Jul

REPOSITORIES: biostudies-literature

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Antiplatelet and anticoagulant agents for primary prevention of thrombosis in individuals with antiphospholipid antibodies.

Bala Malgorzata M MM Paszek Elżbieta E Lesniak Wiktoria W Wloch-Kopec Dorota D Jasinska Katarzyna K Undas Anetta A

The Cochrane database of systematic reviews 20180713

<h4>Background</h4>Antiphospholipid syndrome (APS) is an autoimmune disease characterised by the presence of antiphospholipid (aPL) antibodies that have prothrombotic activity. Antiphospholipid antibodies are associated with an increased risk of pregnancy complications (recurrent miscarriage, premature birth, intrauterine growth retardation) and thrombotic events (both arterial and venous). The most common thrombotic events include brain ischaemia (stroke or transient ischaemic attack) and deep ...[more]

PMID: 30004572

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