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Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome.


ABSTRACT:

SUBMITTER: Bala MM 

PROVIDER: S-EPMC6485894 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature

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Antiplatelet and anticoagulant agents for secondary prevention of stroke and other thromboembolic events in people with antiphospholipid syndrome.

Bala Malgorzata M MM   Celinska-Lowenhoff Magdalena M   Szot Wojciech W   Padjas Agnieszka A   Kaczmarczyk Mateusz M   Swierz Mateusz J MJ   Undas Anetta A  

The Cochrane database of systematic reviews 20171002


<h4>Background</h4>Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by arterial or venous thrombosis (or both) and/or pregnancy morbidity in association with the presence of antiphospholipid antibodies. The prevalence is estimated at 40 to 50 cases per 100,000 people. The most common sites of thrombosis are cerebral arteries and deep veins of the lower limbs. People with a definite APS diagnosis have an increased lifetime risk of recurrent thrombotic events.<h4>Obje  ...[more]

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