Ontology highlight
ABSTRACT:
SUBMITTER: Sakagami M
PROVIDER: S-EPMC6525281 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Sakagami Masaharu M Ouji Yukiteru Y Kawai Norikazu N Misu Masayasu M Yoshikawa Masahide M Kitahara Tadashi T
Biochemistry and biophysics reports 20190515
Vestibular hair cells (V-HCs) in the inner ear have important roles and various functions. When V-HCs are damaged, crippling symptoms, such as vertigo, visual field oscillation, and imbalance, are often seen. Recently, several studies have reported differentiation of embryonic stem (ES) cells, as pluripotent stem cells, to HCs, though a method for producing V-HCs has yet to be established. In the present study, we used vestibular cell conditioned medium (V-CM) and effectively induced ES cells to ...[more]