Ontology highlight
ABSTRACT:
SUBMITTER: Leyva-Castillo JM
PROVIDER: S-EPMC6531322 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Immunity 20190423 5
Mast cell (MC) mediator release after crosslinking of surface-bound IgE antibody by ingested antigen underlies food allergy. However, IgE antibodies are not uniformly associated with food allergy, and intestinal MC load is an important determinant. Atopic dermatitis (AD), characterized by pruritis and cutaneous sensitization to allergens, including foods, is strongly associated with food allergy. Tape stripping mouse skin, a surrogate for scratching, caused expansion and activation of small inte ...[more]