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The etiologic origins for chronic obstructive pulmonary disease.

ABSTRACT: COPD, characterized by long-term poorly irreversible airway limitation and persistent respiratory symptoms, has resulted in enormous challenges to human health worldwide, with increasing rates of prevalence, death, and disability. Although its origin was thought to be in the interactions of genetic with environmental factors, the effects of environmental factors on the disease during different life stages remain little known. Without clear mechanisms and radical cure for it, early screening and prevention of COPD seem to be important. In this review, we will discuss the etiologic origins for poor lung function and COPD caused by specific adverse effects during corresponding life stages, as well as try to find new insights and potential prevention strategies for this disease.

SUBMITTER: Huang X

PROVIDER: S-EPMC6549659 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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The etiologic origins for chronic obstructive pulmonary disease.

Huang Xinwei X Mu Xi X Deng Li L Fu Aili A Pu Endong E Tang Tao T Kong Xiangyang X

International journal of chronic obstructive pulmonary disease 20190527

COPD, characterized by long-term poorly irreversible airway limitation and persistent respiratory symptoms, has resulted in enormous challenges to human health worldwide, with increasing rates of prevalence, death, and disability. Although its origin was thought to be in the interactions of genetic with environmental factors, the effects of environmental factors on the disease during different life stages remain little known. Without clear mechanisms and radical cure for it, early screening and ...[more]

PMID: 31213794

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