Ontology highlight
ABSTRACT:
SUBMITTER: Ku KL
PROVIDER: S-EPMC6549960 | biostudies-literature | 2019 May
REPOSITORIES: biostudies-literature
Ku Kuan-Lin KL Wu Yu-Shan YS Wang Chi-Yun CY Hong Ding-Wei DW Chen Zong-Xing ZX Huang Ching-An CA Chu I-Ming IM Lai Po-Liang PL
Royal Society open science 20190508 5
Poly(methyl methacrylate) (PMMA) is the most frequently used bone void filler in orthopedic surgery. However, the interface between the PMMA-based cement and adjacent bone tissue is typically weak as PMMA bone cement is inherently bioinert and not ideal for bone ingrowth. The present study aims to improve the affinity between the polymer and ceramic interphases. By surface modifying nano-sized hydroxyapatite (nHAP) with ethylene glycol and poly(ɛ-caprolactone) (PCL) sequentially via a two-step r ...[more]