Ontology highlight
ABSTRACT:
SUBMITTER: Zhang T
PROVIDER: S-EPMC3623944 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Journal of immunology (Baltimore, Md. : 1950) 20130123 4
Because NK cells lack gene-recombination machinery and are thought to be relatively short-lived, it is unclear whether NK cells can mount long-term effective recall responses to reinfections by diverse pathogens. In this article, we report that FcRγ-deficient NK cells, which we recently identified and termed g(-)NK cells, possess distinct memory features directed by FcR-mediated Ab-dependent target recognition. The presence of g(-)NK cells was associated with prior human CMV (HMCV) infection, ye ...[more]