Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC6581703 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Li Sha S Tan Hor-Yue HY Wang Ning N Feng Yigang Y Wang Xuanbin X Feng Yibin Y
Frontiers in immunology 20190612
Accumulating clinical and experimental evidences have demonstrated that both innate and adaptive immunity are involved in the pathogenesis of alcoholic liver disease (ALD), in which the role of immunity is to fuel the inflammation and to drive the progression of ALD. Various immune cells are implicated in the pathogenesis of ALD. The activation of innate immune cells induced by alcohol and adaptive immune response triggered by oxidative modification of hepatic constituents facilitate the persist ...[more]