Ontology highlight
ABSTRACT:
SUBMITTER: Sorrells SF
PROVIDER: S-EPMC6588589 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Sorrells Shawn F SF Paredes Mercedes F MF Velmeshev Dmitry D Herranz-Pérez Vicente V Sandoval Kadellyn K Mayer Simone S Chang Edward F EF Insausti Ricardo R Kriegstein Arnold R AR Rubenstein John L JL Manuel Garcia-Verdugo Jose J Huang Eric J EJ Alvarez-Buylla Arturo A
Nature communications 20190621 1
The human amygdala grows during childhood, and its abnormal development is linked to mood disorders. The primate amygdala contains a large population of immature neurons in the paralaminar nuclei (PL), suggesting protracted development and possibly neurogenesis. Here we studied human PL development from embryonic stages to adulthood. The PL develops next to the caudal ganglionic eminence, which generates inhibitory interneurons, yet most PL neurons express excitatory markers. In children, most P ...[more]