Ontology highlight
ABSTRACT:
SUBMITTER: Hu C
PROVIDER: S-EPMC6590035 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Hu Cheng C Jiang Rilei R Cheng Ziyu Z Lu Yueyang Y Gu Ling L Li Hongxiao H Li Liqiu L Gao Qian Q Chen Meijuan M Zhang Xu X
Journal of Cancer 20190602 13
Ophiopogonin-B (OP-B) has been reported to suppress metastasis and angiogenesis of adenocarcinoma A549 cells <i>in vitro</i> and <i>in vivo</i>. More and more evidences indicate that inflammatory microenvironment facilitates tumor metastasis. Digital Gene Expression (DGE) analysis of non-small cell lung cancer (NSCLC) cell lines showed that OP-B downregulated the expression of linc00668, which promoted progression of cancer. Herein, we simulated the inflammatory microenvironment by co-culturing ...[more]