Ontology highlight
ABSTRACT:
SUBMITTER: Chen L
PROVIDER: S-EPMC6596299 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Chen Lin L Huang Shuai S Li Chun Ying CY Gao Feng F Zhou Xian Li XL
Phytochemistry 20180629
Seven pyrrolizidine alkaloids, nervosine X-XV and nervosine VII N-oxide, together with a reaction product, namely chloride-(N-chloromethyl nervosine VII), were isolated from Liparis nervosa. Their structures were elucidated by extensive spectroscopic analyses. Most of these compounds were investigated for their cytotoxicity in vitro against HCT116 human cancer cell line, and the results showed that chloride-(N-chloromethyl nervosine VII) induced tumor cell death in a dose-dependent manner. Furth ...[more]