Ontology highlight
ABSTRACT:
SUBMITTER: Liu Q
PROVIDER: S-EPMC6599589 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Liu Qian Q Zhang Yunxiang Y Peng Chunte Sam CS Yang Tianshe T Joubert Lydia-Marie LM Chu Steven S
Nature photonics 20180806 9
Lanthanide-doped upconversion nanoparticles (UCNPs) are promising single-molecule probes given their non-blinking, photobleach-resistant luminescence upon infrared excitation. However, the weak luminescence of sub-50 nm UCNPs limits their single-particle detection to above 10 kWcm<sup>-2</sup> that is impractical for live cell imaging. Here, we systematically characterize single-particle luminescence for UCNPs with various formulations over a 10<sup>6</sup> variation in incident power, down to 8 ...[more]