Ontology highlight
ABSTRACT:
SUBMITTER: Guo G
PROVIDER: S-EPMC6608635 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Guo Gongrui G Zhu Ping P Fuchs Martin R MR Shi Wuxian W Andi Babak B Gao Yuan Y Hendrickson Wayne A WA McSweeney Sean S Liu Qun Q
IUCrJ 20190503 Pt 4
<i>De novo</i> structural evaluation of native biomolecules from single-wavelength anomalous diffraction (SAD) is a challenge because of the weakness of the anomalous scattering. The anomalous scattering from relevant native elements - primarily sulfur in proteins and phospho-rus in nucleic acids - increases as the X-ray energy decreases toward their <i>K</i>-edge transitions. Thus, measurements at a lowered X-ray energy are promising for making native SAD routine and robust. For microcrystals w ...[more]