Ontology highlight
ABSTRACT:
SUBMITTER: Di Lorenzo B
PROVIDER: S-EPMC6609709 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Di Lorenzo Biagio B Ravens Sarina S Silva-Santos Bruno B
Scientific data 20190704 1
γδ T cells are a relatively rare subset of lymphocytes in the human peripheral blood, but they play important roles at the interface between the innate and the adaptive immune systems. The γδ T cell lineage is characterized by a signature γδ T cell receptor (γδTCR) that displays extensive sequence variability originated by DNA rearrangement of the corresponding V(D)J loci. Human γδ T cells comprise Vγ9Vδ2 T cells, the major subset in the peripheral blood; and Vδ1<sup>+</sup> T cells, the predomi ...[more]