Ontology highlight
ABSTRACT:
SUBMITTER: Gao H
PROVIDER: S-EPMC6616369 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Gao Hui H Chen Jiwang J Chen Tianji T Wang Yifang Y Song Yang Y Dong Yangbasai Y Zhao Shuangping S Machado Roberto F RF
Scientific reports 20190709 1
Nicotinamide phosphoribosyltransferase (NAMPT) upregulation in human pulmonary artery endothelial cells (hPAECs) is associated with pulmonary arterial hypertension (PAH) progression and pulmonary vascular remodeling. The underlying mechanisms regulating NAMPT expression are still not clear. In this study, we aimed to study the regulation of NAMPT expression by microRNA410 (miR410) in hPAECs and explore the role of miR410 in the pathogenesis of experimental pulmonary hypertension. We show that mi ...[more]