Ontology highlight
ABSTRACT:
SUBMITTER: Nieves-Quinones Y
PROVIDER: S-EPMC6628261 | biostudies-literature | 2019 Jun
REPOSITORIES: biostudies-literature
Journal of the American Chemical Society 20190613 25
A highly chemoselective phenol cross-coupling reaction catalyzed by a Cr-salen catalyst was developed. Kinetic studies showed that the oxidation of Cr(III) to Cr(V) is the rate-determining step of the reaction. In addition, experimental stoichiometric analysis showed that a high valent Cr(V) species is the active catalyst for this process. The selectivity of the reaction was found to be determined by the cross-coupling carbon-carbon bond forming reaction, rather than any precoordination species. ...[more]