Ontology highlight
ABSTRACT:
SUBMITTER: Iwasaki F
PROVIDER: S-EPMC6641137 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
ACS omega 20170412 4
The use of achiral surfactant assemblies as a reaction platform for an alkylation reaction resulted in a high enantiomeric excess. Dilauryldimethylammonium bromide (DDAB) vesicles were modified with cholesterol to promote alkylation of <i>N</i>-(diphenylmethylene)glycine <i>tert</i>-butyl ester (DMGBE) with benzyl bromide, resulting in high conversion (∼90%) and high enantioselectivity (up to 80%). The <i>R</i>-enantiomer was formed on using the DDAB vesicles, whereas the use of phospholipid lip ...[more]