Ontology highlight
ABSTRACT:
SUBMITTER: Giomi D
PROVIDER: S-EPMC6641500 | biostudies-literature | 2018 Mar
REPOSITORIES: biostudies-literature
Giomi Donatella D Ceccarelli Jacopo J Brandi Alberto A
ACS omega 20180315 3
The four-step procedure involving bromination, reduction, and nucleophilic substitution via elimination/addition previously applied to 1-(2-pyridyl)-2-propen-1-ol for the synthesis of indolizidine systems has now been extended to 1-(2-quinolyl)-2-propen-1-ol allowing a general access to benzo-fused derivatives. For instance, (±)-benzo[<i>e</i>]lentiginosine has been easily synthesized in an 18% overall yield. ...[more]