Ontology highlight
ABSTRACT:
SUBMITTER: Sahu PK
PROVIDER: S-EPMC6643823 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
ACS omega 20181107 11
A facile and efficient protocol has been developed for mild construction of fused pyrimidines via l-proline-catalyzed reaction of 4-hydroxy coumarins, aldehydes, and 2-aminobenzothiazoles/urea. The reaction has been carried out rapidly and efficiently in water under mild and metal-free conditions. Current etiquette has efficiently synthesized the heterocycles and avoids the use of hazardous solvents over conventional organic solvents. A plausible reaction mechanism has been established in this s ...[more]