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Synthesis of Indoles and Benzofurans Using a Graphene Oxide-Grafted Aminobisphosphine-PdII Complex.


ABSTRACT: Indoles and benzofurans have been synthesized using a graphene oxide-grafted aminobisphosphine-PdII complex (GO@PNP-Pd) under copper-free condition. A range of indole and benzofuran derivatives have been made by the reaction of N-protected 2-iodoanilines and 2-iodophenols with terminal acetylenes in presence of GO@PNP-Pd. The activity of the aminobisphosphine-PdII complex remains the same under both homogeneous and heterogeneous conditions. Finally, the recycling ability of the immobilized catalyst (GO@PNP-Pd) has been examined for five consecutive runs with appreciable conversion.

SUBMITTER: Sengupta D 

PROVIDER: S-EPMC6644095 | biostudies-literature |

REPOSITORIES: biostudies-literature

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