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Chiral Pentacarboxycyclopentadiene-Based Bronsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles.

ABSTRACT: Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Brønsted acid in combination of N-isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products.

SUBMITTER: Yuan C

PROVIDER: S-EPMC6644688 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature

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Chiral Pentacarboxycyclopentadiene-Based Brønsted Acid-Catalyzed Enantioselective Desymmetrization of Meso-Epoxides by 2-Mercaptobenzothiazoles.

Yuan Chao C Li Jun J Li Pingfan P

ACS omega 20180625 6

Enantioselective desymmetrization of meso-epoxides by 2-mercaptobenzothiazoles was realized by using the pentacarboxycyclopentadiene-based chiral Brønsted acid in combination of <i>N</i>-isopropylaniline as amine additive to give up to 90.5:9.5 er of the ring opening products. ...[more]

PMID: 31458851

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